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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a9e8f5be63a6a32c94a4d820b35e35322bd690bd4684222efac86f912bc9a7' 
  AND token = 'Lu02RL6xQoYkKCRfeUWEaB1BywCkn8hyPXIWpdXmJ5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}