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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e220264470cde13e44953211152c9389fb859d3b55fcd9b8abf2336bc241b11a' 
  AND token = '4zeA3+By5tT2YmAx54/elhXLtoFTK92m2FsAiCKlpdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}