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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efae018b6b274442c95c8fd1aaaa26ffcaa8246ad9a50f9c68001a90f320a8c1' 
  AND token = '4Czsh1lqSXT2CezFjh9gJB1YGbKg+q58tLObVmL1Ql0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}