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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de863383ab18ecbc7c0b8b41cf3089a6b7454cb00844171c47b8a661cab2c0f4' 
  AND token = 'nD1eR6P5POGnUO1rYOWz0jxvyAnTbYsOAKl4DrB2Aaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}