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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8778b19146a3f4fe7395ab9f73531134ea7bc6cc2fb655d8dfa38d1832cb66f9' 
  AND token = 'Rz8TMcCz/gaKXIt3dyx5flhigtbeGa5Ra3C/CMKSKEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}