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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0cbc136f53479e362e3d4461c252885c459a4fc5d8ec6139309d94c258193a4' 
  AND token = 'Hr/hQgLH+g1xsnAHj8xQqWvSQ5wr+cQcrINru4NK4fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}