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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5ce005edf5fd8bbc026a78ef15ac27fea5022b73049f4a6aebb5ccde1b545a' 
  AND token = 'Xmn7y1oMpUkEI6Fgi0U9rc0BdN1GI2YqwsJ9NajOHLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}