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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010ec597057f3578f94ed81135599f4c570b6f40bbef3998cc1aae1de66333b6' 
  AND token = '7TNtxUBdhvJro1gyPy6WvCpxAIu+nvfareCcaXaC4TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}