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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c10328a565e11a127a51094fc7071bed16f01deceb4fcda271792e6516fd2f' 
  AND token = 'nr28dee76GWnPHLkTzg+K6QlFqNXuF9uX+4/WyQOHTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}