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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5594b32bbe322747e1edc731e761430e32f022449d7d2835cfca37ac4bc8c9' 
  AND token = 'KMQG63+Xlwh1Vj3FbuZFS3zkasW6TQ28muANGgJbfMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}