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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e777a0196b59c0121df280e2069585de0cf06604845f4d0e5099a03a1d4a43' 
  AND token = 'RsxyOlPE13lUoaehSCK/5tmnerHV+CeArHOq/mUZKzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}