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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e73e52c78948dbd4aa3feebc4e1024815152f7a17266f935d2e5dd69b1059b0' 
  AND token = 'nM5OWLu+XaHq6+Yg42z0YTQ+vxYUY8oocDFxkYqkxnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}