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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bea0faabd25fdae1262589f291886367095efc2dc263c5fdb5ea45e4c94e4b6' 
  AND token = '42mDWyaPxcqRQ9pmvEMexqL6gdhw7TJAsONn063GLIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}