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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecdd548c3754287dddf8f0f3c640a5fa48f08aa43f506852371093f9c4b9c074' 
  AND token = 'd3ohfEggq36sgHUhUMc/d8CS1NNfDvjK7lnvkZmvaA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}