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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459124e42c511e1eaffbfcdd752e077261f33276ba27a419c25ed9f30f1eab1a' 
  AND token = '5CykedTAC45WKsIXwKRNujXZLrTZ7hfka4ASY+UfPO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}