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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03a50580b0e5cd0dd450ce187e875d80af3dcab2f70fe7ee7f2183a654f9d2c' 
  AND token = '+sQ2SV1k7tnynaMQiciaxZBK2EFVWYN2SI2yopeBv+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}