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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8456d676fe608600841838e0755a5587745d7ac8134102e1f1e2ff388d21a7' 
  AND token = 'PhrKPPN7IS4fk8TxfxD/1+GGKKjuvC57l4gft5bLTHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}