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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4dd6cfcb77522f76f1426c337988e00952239a530f8cb078bae23ce303c9e16' 
  AND token = 'zvMKi8pe+YkfoXRwiBL+lFdmaEWwCZb3yWUfBaZAHkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}