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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b7e2d51805bd3cb34ccf878216a06d94212d2defcc0b5576100bca408686860' 
  AND token = '3iIHXTUZcxgDDbDZerZkI0j1PLhLh1qkBUqwOSIpz+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}