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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2502028c9df328c36ffcbe4dadf0cb1cae2e65fe9f87412086a2077a69f498' 
  AND token = 'WX51bj1rmcxwcUTQLXN5rjpJ8b9+2WV13W8+SLM/VS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}