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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00a742886d33607c5f8407946f45b73d7cc0b8f8edc704198e155d2be667141' 
  AND token = 'CBZzeLRsNHsxdXgvPDUsWeu5zssQKyTG8vF6nn9v9bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}