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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2046e428a88c63bc09c4db9600c263362b8625bddd0975d4c6a8e06d8e1cf6a1' 
  AND token = 'EEKh1e7mEzCz55ZTFSvk3uzuYcE0sjo/WqDvZKySkJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}