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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cd4ff4c32342499c0d6cf1a2efc30cb1494c247f6f20575570ce46eba6b7da' 
  AND token = 'b88lxvkyVwlXI4DRylc5e7/2qWlfEE1nL9YQMN00trQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}