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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de2ab488d2d64043783b6002ee6f0cec0fe0b870e4f59167e08a89809d40197' 
  AND token = 'Mq1lUsixbUhqdI2Jg7z7E/7Uoxw6BJbdH02nd/VjqCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}