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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be5b4a21bc72b7a53c975a905b2a8024f883c635e37d8fcfcbfc6e040869046' 
  AND token = '8A5MOc5vRQ267VfdCtZatkG74l3rEZeDN2LTJQBYrxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}