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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c658a18142bf137df7e2066e094dea340ac01f43cc526e8354d5a07b37042b16' 
  AND token = 'RhNmmdj2xL0rpExqM0tp9VBxsZUWZp+FHfj6upSW8mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}