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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a56c9581fe743b471f1861ed4f58d4e6c6294e91cca6313806076344838728' 
  AND token = 'iryZ5BV5HmccZiiP77al/eAuo8qAbg9nC3uOBNei+1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}