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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b688cab1a9cb0749564e52b5022da5e9bbfba4c1fcaa69e59a5f288982831f' 
  AND token = 'pIL0ZqL5+NOw8X839WPvfeFvTfluEEPq6qjQKu3tqQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}