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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d8582b6b4467e546703133cd5f48169626f2b616808c21113b254a53a21495' 
  AND token = 'paUYElE/dHlmXjUf62ywv2uUtcguenOovmXob+2hILs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}