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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e72b4d20a61dd1060b91e7d605eee58e37d0ca332405b82d9cc488c16b7970f' 
  AND token = 'rE4b31hVbtsQlpYlCx0zjzvfPEURxL7shm/s+Mn6ApI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}