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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b40ca521c208b41d4d94c93e1c659de47adfc1a9d65c39a6f57aa7da0e3232' 
  AND token = '+2QCO5SebCnpjj4nEe3H4pp6Q//nLhnxslFAOcdG0PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}