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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161977246f57d6d2f1c8f9375191827547f0d0a99e7c4847ccc4f3cddb2e5c04' 
  AND token = 'AH3CxfcmNcNf2Orww79XipqwGbBZB6Bg4EiGo0tYOEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}