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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39d2dbd857e2361b95e2b445a750af7afe9823f0d35651425ff28e9d0487685' 
  AND token = 'SPMLy58gGeSx3IoJh7uRqkLucOU80Gzogxwloc0j66M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}