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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd51895ea5104dcac90e4985cf2518251c337884bced1418eac12c45b3cf5d2' 
  AND token = 'HUodaor1e/4DYw+bjMno15uX/C2bdCBrwTD7K1b4ia4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}