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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1b11cec4785c0a625d1c652569977da657d989422e77721ae330c13a76ca6d' 
  AND token = 'Iz3DsnyNQl4hRpog1csvO7EHfZyDX7jeDI5a086VSCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}