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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88badf6a6886dc1e47e134830e0ac539665b8b11ba97b0a442b5e9c1c9b37ff' 
  AND token = 'QMt2cK525gCB0wvObeEq0JqFu42Ic8q4OKUTtUM4Gzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}