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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1a130d67c8da1d9abda1d4ec0a38a0f7e5f0048748764f8eb663dd21e2ad48' 
  AND token = 'BCf4sMkwH9xGP9baBvBQJmwOl8OlySKNNJfs5Y6w1vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}