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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fb7889e827eede932ae3b07902f1b566c48f45e8604eb6066e19cf92a742a1' 
  AND token = '4r3eAg93djzad43DW3bYP0XI6R0GlC8cgqA39eu7kco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}