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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a2b00afe113bfd0091c2b4853af5a0faa053e204fc660f9eadbef65fb3c2b4' 
  AND token = 'hBiI3Rp0NaKq0XE7+cv5Y/ovxjZ0yxVHZLz+0cDxNP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}