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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37427ad7c19264397e4a9ebc428c344bb8325b05f06d8f9722d7be9df6319ff' 
  AND token = 'eNQN3YFRSKp5oV/hfvnWWURDi4ttcWMPA3UueYvs3wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}