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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cad1bb6dd316658f52bd06f69dc633d12a0e739086a0ad825d372fe5031a8e3' 
  AND token = 'vG2GcI4UX6/mPlLjqPoYoznS6PhCKjx0AUP9AUYr3bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}