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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efcd5d0cdcaf841e678671c5f1e46d77452df64860e5bba3ebe53e15d7478d9' 
  AND token = 'Qscce21JmxusrqL/5GdQGL1VQ32Ny8ZqzoFgaBjzQ/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}