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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bde01193cd64ab16a24c42eb80d35ac1d974739a6cb6e238bec6ab241c9cf9b' 
  AND token = 'v7mSIy2TF+6z1r4kX+UZYAy7SAJC9fLN+KxFVRlYsa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}