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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '359a2d0cb137b890564d10e5b29fc9262f44d4d68dba03ce859f8072ef6a621a' 
  AND token = 'tMXTo27X7lDXMr+v5D4RZ7sIl9nicVq0f84n+lqK3jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}