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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bbbfa80723ff3170ce392a7e00b3830d06e7e7eb9f6dc5964606791830bf445' 
  AND token = 'Hvv9HLhjcH04Dg/XbjJuLFp4ygAi+cy7Okuz3uMSEK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}