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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0737e3bef4232cec7b831f783e1e336181a8a968b0e2276c1779775de8a0fc9f' 
  AND token = 'kxiaJp3Nh9V48AvRxS6wGpIQl3T9JnyP9kVjRDzUzic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}