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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d60df225e0a7a167133f86e7e194778ab76b9013dbbe422c41d4e261e83d83e' 
  AND token = 'Ntiy4G8eX4qvZfSWanM1bW5Ha1dA3I70Uid7GwZAqCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}