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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33aa7b44e9df83a62d52de324f9f7b463a5c14f3b14dd260a5f04008b165bafd' 
  AND token = '7Lz65AwfvHBuLuy42gB1p+YgGHv0xtaAYjrDHlGVb4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}