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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5981a1be77a9851e8f408fca18deb78c5c9c3f7f1dd769aa2721377c33eef8ac' 
  AND token = 'aI4UHnqV+HQ9QteiqjR7VD7HCSDNccqqSTlo2urLDbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}