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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e289abf8cad6cadb4e4ee6645ec3c8999b04db79f897f0e3b695b2f723b212b7' 
  AND token = 'mxWuK45AFu4Ke/KUZ2jZjyEeplNKENjFGd4LnCPy5gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}